Auditory closed-loop stimulation to manipulate slow-oscillations, a novel approach

Henke, Katharina; Schmidig, Flavio; Ruch, Simon (17 October 2018). Auditory closed-loop stimulation to manipulate slow-oscillations, a novel approach (Unpublished). In: IRC Decoding Sleep Symposium 2018. Bern. 17.10.2018.

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Every day we experience episodes, which we encode effortlessly on the fly by forming what, where and when associations. A recently published experiment of our research group on vocabulary learning during deep sleep suggests that hippocampus-mediated rapid relational encoding is even feasible in a state of unconsciousness such as deep sleep (Züst, Ruch, Wiest, & Henke, 2018). Since hippocampal activity climaxes during up-states of cortical slow-oscillations and slow-oscillations result from alternations between phases of high neuronal activity and plasticity (up-states) and phases of neuronal silence (down-states), our study tested, if the slow-wave phase is crucial for de-novo learning during sleep.
We aimed at enlarging up-states to facilitate sleep-learning using a closed-loop procedure, in which we targeted acoustic stimuli to up-states (versus down-states: control condition) of slow-oscillations during deep sleep. Here, we present preliminary data (n=8).

Item Type:

Conference or Workshop Item (Poster)


07 Faculty of Human Sciences > Institute of Psychology > Weitere Forschungsgruppen

UniBE Contributor:

Henke, Katharina, Schmidig, Flavio Jean, Ruch, Simon


100 Philosophy > 150 Psychology




Flavio Jean Schmidig

Date Deposited:

19 Jan 2023 16:02

Last Modified:

20 Apr 2023 19:03




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