Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours

Boller, Danielle; Doepfner, Kathrin T; De Laurentiis, Angela; Guerreiro, Ana S; Marinov, Marin; Shalaby, Tarek; Depledge, Paul; Robson, Anthony; Saghir, Nahid; Hayakawa, Masahiko; Kaizawa, Hiroyuki; Koizumi, Tomonobu; Ohishi, Takahide; Fattet, Sarah; Delattre, Olivier; Schweri-Olac, Anelia; Höland, Katrin; Grotzer, Michael A; Frei, Karl; Spertini, Olivier; ... (2012). Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours. Anticancer research, 32(8), pp. 3015-27. Kapandriti: International Inst. of Anticancer Research

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Eight human catalytic phosphoinositide 3-kinase (PI3K) isoforms exist which are subdivided into three classes. While class I isoforms have been well-studied in cancer, little is known about the functions of class II PI3Ks.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Höland, Katrin and Arcaro, Alexandre

ISSN:

0250-7005

Publisher:

International Inst. of Anticancer Research

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:40

Last Modified:

06 Dec 2013 13:38

PubMed ID:

22843869

Web of Science ID:

000306892700001

URI:

https://boris.unibe.ch/id/eprint/16511 (FactScience: 224164)

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