High rhinovirus burden in lower airways of children with cystic fibrosis

Kieninger, Elisabeth; Singer, Florian; Tapparel, Caroline; Alves, Marco P; Latzin, Philipp; Tan, Hui-Leng; Bossley, Cara; Casaulta, Carmen; Bush, Andrew; Davies, Jane C; Kaiser, Laurent; Regamey, Nicolas (2013). High rhinovirus burden in lower airways of children with cystic fibrosis. Chest, 143(3), pp. 782-90. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.12-0954

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Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung function parameters in children with CF compared with a control group and children with other chronic respiratory diseases.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Casaulta Aebischer, Carmen; Singer, Florian; Latzin, Philipp and Regamey, Nicolas

ISSN:

0012-3692

Publisher:

American College of Chest Physicians

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:40

Last Modified:

06 Dec 2013 13:38

Publisher DOI:

10.1378/chest.12-0954

PubMed ID:

23188200

Web of Science ID:

000317871300033

URI:

https://boris.unibe.ch/id/eprint/16516 (FactScience: 224169)

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