Body composition assessment: comparison of quantitative values between magnetic resonance imaging and computed tomography.

Zaffina, Chiara; Wyttenbach, Rolf; Pagnamenta, Alberto; Grasso, Rosario Francesco; Biroli, Matteo; Del Grande, Filippo; Rizzo, Stefania (2022). Body composition assessment: comparison of quantitative values between magnetic resonance imaging and computed tomography. Quantitative imaging in medicine and surgery, 12(2), pp. 1450-1466. AME Publishing Company 10.21037/qims-21-619

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Background

The primary objective of this study was to compare measurements of skeletal muscle index (SMI), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) at the level of L3, on subjects who underwent computed tomography (CT) and magnetic resonance imaging (MRI) examinations within a three-month period. The secondary objective was to compare the automatic and semi-automatic quantifications of the same values for CT images.

Methods

Among subjects who underwent CT and MRI at our Institution between 2011 and 2020, exclusion criteria were: presence of extensive artifacts; images not including the whole waist circumference; CT acquired with low-dose technique and lack of non-contrast images. A set of three axial images (CT, MRI T1-weighted and T2-weighted) were used to extract the following measurements with semi-automatic segmentations: SMI [calculated normalizing skeletal muscle area (SMA) by the square height], SAT, VAT. For the CT images only, the same values were also calculated by using automatic segmentation. Statistical analysis was performed comparing quantitative MRI and CT measurements by Pearson correlation analysis and by Bland-Altman agreement analysis.

Results

A total of 123 patients were included. By performing linear regression analysis, CT and MRI measurements of SMI showed a high correlation (r2=0.81 for T1, r2=0.89 for T2), with a mean logarithmic difference between CT and MRI quantitative values of 0.041 for T1-weighted and 0.072 for T2-weighted images. CT and MRI measurements of SAT showed high correlation (r2=0.81 for T1; r2=0.81 for T2), with a mean logarithmic difference between CT and MRI values of 0.0174 for T1-weighted and 0.201 for T2-weighted images. CT and MRI measurements of VAT showed high correlation (r2=0.94 for T1; r2=0.93 for T2), with a mean logarithmic difference of 0.040 for T1-weighted and -0.084 for T2-weighted images. The comparison of values extracted by semi-automatic and automatic segmentations were highly correlated.

Conclusions

Quantification of body composition values at MRI from T1-weighted and T2-weighted images was highly correlated to same values at CT, therefore quantitative values of body composition among patients who underwent either one of the examinations may be compared. CT body composition values extracted by semi-automatic and automatic segmentations showed high correlation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Wyttenbach, Rolf

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2223-4292

Publisher:

AME Publishing Company

Language:

English

Submitter:

Maria de Fatima Henriques Bernardo

Date Deposited:

24 Feb 2022 15:57

Last Modified:

10 May 2024 10:42

Publisher DOI:

10.21037/qims-21-619

PubMed ID:

35111638

Uncontrolled Keywords:

Body composition computed tomography (CT) magnetic resonance imaging (MRI)

BORIS DOI:

10.48350/165242

URI:

https://boris.unibe.ch/id/eprint/165242

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