[Arterial-ischaemic stroke in childhood]

Goeggel Simonetti, Barbara; Steinlin, M; Arnold, M; Fischer, Urs (2012). [Arterial-ischaemic stroke in childhood]. Therapeutische Umschau, 69(9), pp. 536-542. Bern: Huber 10.1024/0040-5930/a000326

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The risk to have a stroke during childhood is at least as frequent as to suffer from a brain tumour. Unlike adults, in whom ischaemic strokes overweigh haemorrhagic strokes, ischaemic and haemorrhagic strokes are equally frequent in children, occurring with an incidence of 2 - 3/100'000 children/year. Even though the clinical presentation of arterial-ischaemic stroke in children (pedAIS) is similar to adults, time to diagnosis is longer. The delay to diagnosis is mainly explained by the low index of suspicion of both the general population and the medical personnel, a broad range of differential diagnoses, and the fact that diagnostic imaging in children often requires sedation, which is not always readily available. PedAIS is a multiple risk problem, usually occurring due to a combination of risk factors, such as infectious diseases, dehydration, trauma or an underlying condition such as congenital heart disease. Still little is known about the appropriate management of pedAIS. Supportive measures are considered to be the mainstay of therapy. The use of antithrombotic medication depends on pedAIS aetiology. In an ongoing multicenter trial, the safety and effectiveness of thrombolysis are currently being investigated. PedAIS carries an important mortality and morbidity, with neurological and neuropsychological deficits persisting in two thirds of the affected children.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
UniBE Contributor:	Goeggel Simonetti, Barbara, Steinlin, Maja, Arnold, Marcel, Fischer, Urs Martin
Subjects:	600 Technology > 610 Medicine & health
ISSN:	0040-5930
ISBN:	0040-5930 (Print);00
Publisher:	Huber
Language:	German
Submitter:	Anette van Dorland
Date Deposited:	04 Oct 2013 14:41
Last Modified:	02 Mar 2023 23:21
Publisher DOI:	10.1024/0040-5930/a000326
PubMed ID:	22923357
URI:	https://boris.unibe.ch/id/eprint/16534 (FactScience: 224188)