Editorial: Second-Generation Antipsychotics for Bipolar Depression in Youths: The Best Evidence Synthesis Is a Strong Call for Further Evidence.

Cortese, Samuele; Frazier, Jean A; Del Giovane, Cinzia (2022). Editorial: Second-Generation Antipsychotics for Bipolar Depression in Youths: The Best Evidence Synthesis Is a Strong Call for Further Evidence. Journal of the American Academy of Child & Adolescent Psychiatry, 61(2), pp. 128-130. Elsevier 10.1016/j.jaac.2021.07.004

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Before the network meta-analysis (NMA) by DelBello et al. in this issue of the Journal, no NMA had been published on the pharmacological treatment of bipolar depression in youths. DelBello et al. have filled this gap by conducting the first NMA of second-generation antipsychotics for major depressive episodes in youths with bipolar disorder. The NMA by DelBello et al. is arguably the best available evidence synthesis on the comparative efficacy and safety of second-generation antipsychotics for bipolar depression in youths. However, it should be considered as the first building block that strongly calls for more evidence to support clinical decision making in the management of this serious but overlooked condition.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Del Giovane, Cinzia

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0890-8567

Publisher:

Elsevier

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

17 Feb 2022 17:56

Last Modified:

05 Dec 2022 16:09

Publisher DOI:

10.1016/j.jaac.2021.07.004

PubMed ID:

34273494

BORIS DOI:

10.48350/165704

URI:

https://boris.unibe.ch/id/eprint/165704

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