International consensus recommendations for eosinophilic gastrointestinal disease nomenclature.

Dellon, Evan S; Gonsalves, Nirmala; Abonia, J Pablo; Alexander, Jeffrey A; Arva, Nicoleta C; Atkins, Dan; Attwood, Stephen E; Auth, Marcus Kh; Bailey, Dominique D; Biederman, Luc; Blanchard, Carine; Bonis, Peter A; Bose, Paroma; Bredenoord, Albert J; Chang, Joy W; Chehade, Mirna; Collins, Margaret H; Di Lorenzo, Carlo; Dias, Jorge Amil; Dohil, Ranjan; ... (2022). International consensus recommendations for eosinophilic gastrointestinal disease nomenclature. Clinical gastroenterology and hepatology, 20(11), 2474-2484.e3. Elsevier 10.1016/j.cgh.2022.02.017

Preview	Text 1-s2.0-S1542356522001434-main.pdf - Accepted Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (1MB) | Preview
	Text Dellon_ClinGastroenterolHepatol_2022.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (886kB)

BACKGROUND & AIMS

Substantial heterogeneity in terminology used for eosinophilic gastrointestinal diseases (EGID), particularly the catchall term "eosinophilic gastroenteritis", limits clinical and research advances. We aimed to achieve an international consensus for standardized EGID nomenclature.

METHODS

This consensus process utilized Delphi methodology. An initial naming framework was proposed and refined in iterative fashion, then assessed in a first round of Delphi voting. Results were discussed in two consensus meetings, the framework was updated, and re-assessed in a second Delphi vote, with a 70% threshold set for agreement.

RESULTS

Of 91 experts participating, 85 (93%) completed the first and 82 (90%) completed the second Delphi surveys. Consensus was reached on all but two statements. "EGID" was the preferred umbrella term for disorders of GI tract eosinophilic inflammation in the absence of secondary causes (100% agreement). Involved GI tract segments will be named specifically and use an "Eo" abbreviation convention: eosinophilic gastritis (now abbreviated EoG), eosinophilic enteritis (EoN), and eosinophilic colitis (EoC). The term "eosinophilic gastroenteritis" is no longer preferred as the overall name (96% agreement). When >2 GI tract areas are involved, the name should reflect all of the involved areas.

CONCLUSIONS

This international process resulted in consensus for updated EGID nomenclature for both clinical and research use. EGID will be the umbrella term rather than "eosinophilic gastroenteritis", and specific naming conventions by location of GI tract involvement are recommended. As more data are developed, this framework can be updated to reflect best practices and the underlying science.

Interest & Impact

Downloads

132 since deposited on 21 Feb 2022
102 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item