Wald, Caroline Sophie; Unterlauft, Jan Darius; Rehak, Matus; Girbardt, Christian (2022). Retinometer predicts visual outcome in Descemet membrane endothelial keratoplasty. Graefe's archive for clinical and experimental ophthalmology, 260(7), pp. 2283-2290. Springer 10.1007/s00417-022-05605-w
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PURPOSE
To analyze the preoperative predictive value of retinometer visual acuity (VA) in eyes following Descemet membrane endothelial keratoplasty (DMEK).
METHODS
Patients undergoing DMEK between August 2011 and July 2020 were included. Preoperative interference visual acuity was assessed using Heine Lambda 100 Retinometer. Depending on the presence or absence of concomitant ocular disease, the Retinometer was evaluated for its ability to preoperatively predict best-corrected visual acuity (BCVA) six months after surgery using correlation, simple and multiple linear regression, contingency analyses, and receiver operating characteristic (ROC) analysis. Preoperative corneal backscatter was correlated with Retinometer prediction accuracy.
RESULTS
A total of 198 eyes were included in the analysis. There was a significant correlation between Retinometer VA and postoperative BCVA (r = 0.647, P < 0.001). Regardless of the presence or absence of concomitant ocular disease and the surgery procedure (DMEK & triple DMEK), Retinometer VA was the most significant predictor of postoperative BCVA (P < 0.001). ROC analysis revealed reliable diagnostic performance of the Retinometer (AUC = 0.829, P < 0.001). A Retinometer VA ≥ 0.5 accurately predicted a postoperative BCVA ≥ 0.5 in 91% of cases. No association was found between corneal backscatter and prediction accuracy (P = 0.566).
CONCLUSIONS
Retinometer VA can be used for preoperative prediction of postoperative BCVA in DMEK and triple DMEK patients, independent of increased backscatter values and the presence or absence of concomitant ocular disease. By using this simple but effective tool, indication for DMEK can be facilitated and postoperative outcomes can be realistically predicted preoperatively.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Unterlauft, Jan Darius |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0721-832X |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
28 Feb 2022 12:48 |
Last Modified: |
05 Dec 2022 16:11 |
Publisher DOI: |
10.1007/s00417-022-05605-w |
PubMed ID: |
35218379 |
Uncontrolled Keywords: |
Corneal transplantation DMEK Interference visual acuity Retinometer |
BORIS DOI: |
10.48350/166118 |
URI: |
https://boris.unibe.ch/id/eprint/166118 |
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