Kirkeby, Carsten; Brookes, Victoria J; Ward, Michael P; Dürr, Salome; Halasa, Tariq (2021). A Practical Introduction to Mechanistic Modeling of Disease Transmission in Veterinary Science. Frontiers in veterinary science, 7, p. 546651. Frontiers Media 10.3389/fvets.2020.546651
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Computer-based disease spread models are frequently used in veterinary science to simulate disease spread. They are used to predict the impacts of the disease, plan and assess surveillance, or control strategies, and provide insights about disease causation by comparing model outputs with real life data. There are many types of disease spread models, and here we present and describe the implementation of a particular type: individual-based models. Our aim is to provide a practical introduction to building individual-based disease spread models. We also introduce code examples with the goal to make these techniques more accessible to those who are new to the field. We describe the important steps in building such models before, during and after the programming stage, including model verification (to ensure that the model does what was intended), validation (to investigate whether the model results reflect the modeled system), and convergence analysis (to ensure models of endemic diseases are stable before outputs are collected). We also describe how sensitivity analysis can be used to assess the potential impact of uncertainty about model parameters. Finally, we provide an overview of some interesting recent developments in the field of disease spread models.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management 05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Public Health Institute 05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) |
UniBE Contributor: |
Dürr, Salome Esther |
Subjects: |
600 Technology 600 Technology > 630 Agriculture |
ISSN: |
2297-1769 |
Publisher: |
Frontiers Media |
Language: |
English |
Submitter: |
Susanne Agnes Lerch |
Date Deposited: |
07 Mar 2022 15:28 |
Last Modified: |
10 Feb 2023 10:28 |
Publisher DOI: |
10.3389/fvets.2020.546651 |
Related URLs: |
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PubMed ID: |
33575275 |
Uncontrolled Keywords: |
disease dynamics disease model mechanistic model simulation model transmission model |
BORIS DOI: |
10.48350/166269 |
URI: |
https://boris.unibe.ch/id/eprint/166269 |
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