Rothenbühler, Simon; Gonzalez, Adrian; Iacovache, Ioan; Langenegger, Simon M.; Zuber, Benoît; Häner, Robert (2022). Tetraphenylethylene–DNA conjugates: influence of sticky ends and DNA sequence length on the supramolecular assembly of AIE-active vesicles. Organic & biomolecular chemistry, 20(18), pp. 3703-3707. Royal Society of Chemistry 10.1039/D2OB00357K
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The supramolecular assembly of DNA conjugates, functionalized with tetraphenylethylene (TPE) sticky ends, into vesicular structures is described. The aggregation-induced emission (AIE) active TPE units allow to monitor the assembly process by fluorescence spectroscopy. The number of TPE modifications in the overhangs of the conjugates influences the supramolecular assembly behavior. A minimum of two TPE residues on each end are required to ensure a well-defined assembly process. The design of the presented DNA-based nanostructures offers tailored functionalization with applications in DNA nanotechnology.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
09 Interdisciplinary Units > Microscopy Imaging Center (MIC) 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy 08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Rothenbühler, Simon, Iacovache, Mircea Ioan, Langenegger, Simon Matthias, Zuber, Benoît, Häner, Robert |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry 600 Technology > 610 Medicine & health |
ISSN: |
1477-0520 |
Publisher: |
Royal Society of Chemistry |
Funders: |
[42] Schweizerischer Nationalfonds |
Language: |
English |
Submitter: |
Robert Häner |
Date Deposited: |
14 Apr 2022 09:19 |
Last Modified: |
05 Dec 2022 16:13 |
Publisher DOI: |
10.1039/D2OB00357K |
PubMed ID: |
35262542 |
BORIS DOI: |
10.48350/166987 |
URI: |
https://boris.unibe.ch/id/eprint/166987 |
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