Present Practice of Radiative Deep Hyperthermia in Combination with Radiotherapy in Switzerland.

Stutz, Emanuel; Puric, Emsad; Ademaj, Adela; Künzi, Arnaud; Krcek, Reinhardt; Timm, Olaf; Marder, Dietmar; Notter, Markus; Rogers, Susanne; Bodis, Stephan; Riesterer, Oliver (2022). Present Practice of Radiative Deep Hyperthermia in Combination with Radiotherapy in Switzerland. Cancers, 14(5), p. 1175. MDPI AG 10.3390/cancers14051175

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BACKGROUND

Moderate hyperthermia is a potent and evidence-based radiosensitizer. Several indications are reimbursed for the combination of deep hyperthermia with radiotherapy (dHT+RT). We evaluated the current practice of dHT+RT in Switzerland.

METHODS

All indications presented to the national hyperthermia tumor board for dHT between January 2017 and June 2021 were evaluated and treatment schedules were analyzed using descriptive statistics.

RESULTS

Of 183 patients presented at the hyperthermia tumor board, 71.6% were accepted and 54.1% (99/183) finally received dHT. The most commonly reimbursed dHT indications were "local recurrence and compression" (20%), rectal (14.7%) and bladder (13.7%) cancer, respectively. For 25.3% of patients, an individual request for insurance cover was necessary. 47.4% of patients were treated with curative intent; 36.8% were in-house patients and 63.2% were referred from other hospitals.

CONCLUSIONS

Approximately two thirds of patients were referred for dHT+RT from external hospitals, indicating a general demand for dHT in Switzerland. The patterns of care were diverse with respect to treatment indication. To the best of our knowledge, this study shows for the first time the pattern of care in a national cohort treated with dHT+RT. This insight will serve as the basis for a national strategy to evaluate and expand the evidence for dHT.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR)

UniBE Contributor:

Stutz, Emanuel, Künzi, Arnaud Yi-Yao, Krcek, Reinhardt

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2072-6694

Publisher:

MDPI AG

Language:

English

Submitter:

Pubmed Import

Date Deposited:

11 Mar 2022 11:04

Last Modified:

20 Feb 2024 14:16

Publisher DOI:

10.3390/cancers14051175

PubMed ID:

35267486

Uncontrolled Keywords:

deep hyperthermia moderate hyperthermia patterns of care radiative hyperthermia radiotherapy reimbursement

BORIS DOI:

10.48350/167214

URI:

https://boris.unibe.ch/id/eprint/167214

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