[Polypharmacy and inappropriate medications in multimorbid elderly patients - What OPERAM taught us and will teach us].

Bretagne, Lisa; Jungo, Katharina Tabea; Blum, Manuel R; Schwenkglenks, Matthias; Chiolero, Arnaud; Del Giovane, Cinzia; Gencer, Baris; Aujesky, Drahomir; Rodondi, Nicolas (2022). [Polypharmacy and inappropriate medications in multimorbid elderly patients - What OPERAM taught us and will teach us]. Revue médicale suisse, 18(772), pp. 427-432. Médecine & Hygiène 10.53738/REVMED.2022.18.772.427

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Polypharmacy and inappropriate medication use are very common in multimorbid older patients. This population has unfortunately been excluded from most large, randomized studies. In a recent multicenter randomized study (OPERAM), we included over 2000 multimorbid patients. We found that 86% of the patients aged 70 years and more had inappropriate medications and that these medications could be discontinued without negative impact on the health of these patients. This cohort of multimorbid patients will be followed for 10 years to evaluate their prognosis, life expectancy, treatments and quality of life, with numerous projects to better understand the inappropriate prescribing of individual drugs and their consequences on the health of this population.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine

UniBE Contributor:

Bretagne, Lisa; Jungo, Katharina Tabea; Blum, Manuel; Chiolero, Arnaud; Del Giovane, Cinzia; Gencer, Baris Faruk; Aujesky, Drahomir and Rodondi, Nicolas

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0025-6749

Publisher:

Médecine & Hygiène

Language:

French

Submitter:

Pubmed Import

Date Deposited:

11 Mar 2022 10:45

Last Modified:

22 Mar 2022 09:36

Publisher DOI:

10.53738/REVMED.2022.18.772.427

PubMed ID:

35266342

URI:

https://boris.unibe.ch/id/eprint/167216

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