[Polypharmacy and inappropriate medications in multimorbid elderly patients - What OPERAM taught us and will teach us].

Bretagne, Lisa; Jungo, Katharina Tabea; Blum, Manuel R; Schwenkglenks, Matthias; Chiolero, Arnaud; Del Giovane, Cinzia; Gencer, Baris; Aujesky, Drahomir; Rodondi, Nicolas (2022). [Polypharmacy and inappropriate medications in multimorbid elderly patients - What OPERAM taught us and will teach us]. Revue médicale suisse, 18(772), pp. 427-432. Médecine & Hygiène 10.53738/REVMED.2022.18.772.427

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Polypharmacy and inappropriate medication use are very common in multimorbid older patients. This population has unfortunately been excluded from most large, randomized studies. In a recent multicenter randomized study (OPERAM), we included over 2000 multimorbid patients. We found that 86% of the patients aged 70 years and more had inappropriate medications and that these medications could be discontinued without negative impact on the health of these patients. This cohort of multimorbid patients will be followed for 10 years to evaluate their prognosis, life expectancy, treatments and quality of life, with numerous projects to better understand the inappropriate prescribing of individual drugs and their consequences on the health of this population.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine 04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM) 04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine
UniBE Contributor:	Bretagne, Lisa, Jungo, Katharina Tabea, Blum, Manuel, Chiolero, Arnaud, Del Giovane, Cinzia, Gencer, Baris Faruk, Aujesky, Drahomir, Rodondi, Nicolas
Subjects:	600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services
ISSN:	0025-6749
Publisher:	Médecine & Hygiène
Language:	French
Submitter:	Pubmed Import
Date Deposited:	11 Mar 2022 10:45
Last Modified:	05 Dec 2022 16:14
Publisher DOI:	10.53738/REVMED.2022.18.772.427
PubMed ID:	35266342
URI:	https://boris.unibe.ch/id/eprint/167216