Targeted Medical History and Diagnostic Testing in Uveitis.

Grajewski, Rafael S; Tappeiner, Christoph; Thurau, Stephan (2022). Targeted Medical History and Diagnostic Testing in Uveitis. Klinische Monatsblätter für Augenheilkunde, 239(5), pp. 654-658. Thieme 10.1055/a-1737-4306

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Uveitis is a collective term for a variety of different intraocular inflammations. The underlying etiologies vary greatly depending on the uveitis subtype, and in particular the anatomical focus. The most common forms of anterior uveitis are acute fibrinous unilateral uveitis, often associated with the HLA-B27 haplotype, and granulomatous inflammation, typically associated with sarcoidosis or herpes infections. Intermediate uveitis is usually idiopathic in nature but can also be associated with multiple sclerosis or sarcoidosis, while vitreoretinal lymphoma must also be considered as a masquerade syndrome in patients aged over 45. Posterior uveitis, on the other hand, as well as retinal vasculitis and panuveitis, have a very broad variety of etiologies; these can, however, be narrowed down through a similar findings-centered approach. Retinitis, for example, is often associated with infections (Toxoplasma gondii and viruses of the herpes group), whereas chorioditis is frequently idiopathic, although infections such as tuberculosis may occur. Therefore, the medical history and laboratory diagnosis should be tailored in patients with uveitis based on the anatomic focus of inflammation (anterior, intermediate, or posterior uveitis, or panuveitis) and the clinical picture (e.g., granulomatous versus nongranulomatous).

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Tappeiner, Christoph

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1439-3999

Publisher:

Thieme

Language:

English

Submitter:

Pubmed Import

Date Deposited:

24 Mar 2022 10:44

Last Modified:

11 May 2023 10:52

Publisher DOI:

10.1055/a-1737-4306

PubMed ID:

35320872

URI:

https://boris.unibe.ch/id/eprint/167938

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