A Retrospective Analysis of Multiple Affected Salivary Gland Diseases: Diagnostic and Therapeutic Benefits of Interventional Sialendoscopy.

Borner, Urs; Anschuetz, Lukas; Caversaccio, Marco; von Werdt, Moritz; Panosetti, Eugène; Keghian, Jérôme; Remacle, Marc (2022). A Retrospective Analysis of Multiple Affected Salivary Gland Diseases: Diagnostic and Therapeutic Benefits of Interventional Sialendoscopy. (In Press). Ear, nose, & throat journal, p. 1455613221081911. Sage 10.1177/01455613221081911

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OBJECTIVES

Multiple affected salivary gland diseases are rare compared to single gland diseases and represent a major diagnostic challenge. These cases are commonly neglected in the scientific literature, despite the considerable suffering of these patients. The aim of this retrospective study was to report disease characteristics, diagnostic pathways, and therapeutic options, including sialendoscopic treatment of multiple affected salivary gland disorders.

METHODS

Patients experiencing multiple affected salivary gland diseases treated between 2013 and 2020 were consecutively identified. Data regarding demographics, clinical presentation, disease characteristics, treatment, complications, and follow-up were analyzed retrospectively.

RESULTS

In total, 71 patients were identified with these diseases and included obstructive disease without sialolithiasis (n = 22), inflammation (n = 15), immune disease (n = 19), radioiodine-induced sialadenitis (RAI) (n = 5), sialadenosis (n = 2), and juvenile recurrent parotitis (JRP) (n = 8). Diagnostic and therapeutic sialendoscopy was performed on 113 salivary glands in 42 patients, leading to completely (n = 27, 64.3%) or partially (n = 11, 26.2%) improved symptoms in most cases. In total, 4 patients did not improve after interventional therapy.

CONCLUSIONS

Multiple affected salivary gland diseases are rare and diagnostically challenging. Interventional sialendoscopy offers an effective and safe therapeutic option and should be considered in this specific cohort.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Borner, Urs, Anschütz, Lukas Peter, Caversaccio, Marco, Von Werdt, Moritz

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1942-7522

Publisher:

Sage

Language:

English

Submitter:

Pubmed Import

Date Deposited:

25 Mar 2022 10:08

Last Modified:

05 Dec 2022 16:16

Publisher DOI:

10.1177/01455613221081911

PubMed ID:

35324340

Uncontrolled Keywords:

multiple affected salivary glands salivary gland sialendoscopy ultrasonography

BORIS DOI:

10.48350/168030

URI:

https://boris.unibe.ch/id/eprint/168030

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