Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole

Zawodniak, A.; Lochmatter, P.; Beeler, A.; Pichler, W. J. (2010). Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole. International archives of allergy and immunology, 153(2), pp. 152-156. Basel: Karger 10.1159/000312632

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Sulfonamides are generally classified into 2 groups: antibiotics and non-antibiotics. Recent studies showed that patients allergic to sulfonamide antibiotics do not have a specific risk for an allergy to sulfonamide non-antibiotic. However, the anti-inflammatory drug sulfasalazine represents an important exception. Used in rheumatic diseases, it is classified as a non-antibiotic sulfonamide, but is structurally related to antibiotic sulfonamides. Therefore, we aimed to analyze in vitro the cross-reactivity between the antimicrobial sulfamethoxazole and the anti-inflammatory drug sulfasalazine.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Gschwend, Anna and Pichler, Werner Joseph

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1018-2438

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:10

Last Modified:

01 Feb 2021 11:16

Publisher DOI:

10.1159/000312632

PubMed ID:

20413982

Web of Science ID:

000279596400006

URI:

https://boris.unibe.ch/id/eprint/1687 (FactScience: 203567)

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