Catheter-Directed Thrombolysis for Postpartum Deep Venous Thrombosis

Girona, Miguel; Säly, Christoph; Makaloski, Vladimir; Baumgartner, Iris; Schindewolf, Marc (2022). Catheter-Directed Thrombolysis for Postpartum Deep Venous Thrombosis. Frontiers in cardiovascular medicine, 9 Frontiers 10.3389/fcvm.2022.814057

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Venous thromboembolism is a major concern during pregnancy as well as in
the postpartum period. In acute proximal deep venous thrombosis, endovascular
recanalization with locally administered thrombolytic agents has evolved as therapeutic
alternative to anticoagulation alone. However, data on the bleeding risk of thrombolysis
in the postpartum period is limited. We addressed the key clinical question of
safety outcomes of catheter-directed thrombolysis (CDT) in the peri- and postpartum
period. Therefore, we performed a non-exhaustive literature review and illustrated the
delicate management of a patient with postpartum acute iliofemoral thrombosis treated
with CDT and endovascular revascularization with thrombectomy, balloon angioplasty
and stenting.

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