Fuchs Syndrome with Isolated Oral Mucosa Lesions due to Severe Herpes Simplex Cheilitis in a Patient with Idiopathic Thrombocytopenic Purpura.

Eyer, Gian-Carlo; Heidemeyer, Kristine; Exadaktylos, Aristomenis; Ziaka, Mairi (2022). Fuchs Syndrome with Isolated Oral Mucosa Lesions due to Severe Herpes Simplex Cheilitis in a Patient with Idiopathic Thrombocytopenic Purpura. European journal of case reports in internal medicine, 9(4), 003278. SMC Media 10.12890/2022_003278

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Stevens-Johnson syndrome (SJS) is a severe dermatological disease classically characterized by erythematous target lesions and mucosal involvement. Fuchs syndrome is an incomplete presentation of SJS which has oral, conjunctival and genital manifestations but no skin lesions. To the best of our knowledge, our case of Fuchs syndrome in an 80-year-old man is the first such case related to herpes simplex virus (HSV)-1 infection to be described. Our patient quickly recovered following IVIG therapy, although specific treatment is still a topic of discussion. Research is required on this poorly understood dermatological disease to determine optimum therapy.

LEARNING POINTS

We report a case of Fuchs syndrome in an elderly man after HSV-1 cheilitis.Therapy always includes discontinuation of the causative drug.Specific therapy for Stevens-Johnson syndrome and Fuchs syndrome is still a topic of discussion, although we noted marked improvement following the administration of IVIG therapy.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > University Emergency Center
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Heidemeyer, Kristine, Exadaktylos, Aristomenis

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2284-2594

Publisher:

SMC Media

Language:

English

Submitter:

Pubmed Import

Date Deposited:

09 May 2022 13:21

Last Modified:

05 Dec 2022 16:19

Publisher DOI:

10.12890/2022_003278

PubMed ID:

35520365

Uncontrolled Keywords:

Fuchs syndrome herpes simplex cheilitis idiopathic thrombocytopenic purpura

BORIS DOI:

10.48350/169839

URI:

https://boris.unibe.ch/id/eprint/169839

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