Prevalence, predictors, and consequences of long-term refusal of antipsychotic treatment in first-episode psychosis

Lambert, Martin; Conus, Philippe; Cotton, Sue; Robinson, Jo; McGorry, Patrick D; Schimmelmann, Benno G (2010). Prevalence, predictors, and consequences of long-term refusal of antipsychotic treatment in first-episode psychosis. Journal of Clinical Psychopharmacology, 30(5), pp. 565-72. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/JCP.0b013e3181f058a0

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Studies investigating medication adherence in psychosis are limited by the need of a certain degree of medication adherence and the inclusion of mostly multiple-episode patients. By contrast, noninformed consent, epidemiological studies in first-episode psychosis (FEP) allow the assessment of an important subgroup of patients who persistently refuse antipsychotic medication and thereby never receive an adequate antipsychotic trial. The present study aims to assess the prevalence and predictors of such a "medication refusal" subgroup and its association with illness outcome.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy
UniBE Contributor:	Schimmelmann, Benno Karl Edgar
ISSN:	0271-0749
Publisher:	Lippincott Williams & Wilkins
Language:	English
Submitter:	Myriam Pyrlik
Date Deposited:	04 Oct 2013 14:11
Last Modified:	05 Dec 2022 14:01
Publisher DOI:	10.1097/JCP.0b013e3181f058a0
PubMed ID:	20814327
Web of Science ID:	000281846400012
URI:	https://boris.unibe.ch/id/eprint/1704 (FactScience: 203634)