Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention

Oades, Robert D; Myint, Aye-Mu; Dauvermann, Maria R; Schimmelmann, Benno Karl Edgar; Schwarz, Markus J (2010). Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention. Behavioral and brain functions, 6, p. 32. London: BioMed Central 10.1186/1744-9081-6-32

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In contrast to studies of depression and psychosis, the first part of this study showed no major differences in serum levels of cytokines and tryptophan metabolites between healthy children and those with attention-deficit/hyperactivity disorder of the combined type (ADHD). Yet, small decreases of potentially toxic kynurenine metabolites and increases of cytokines were evident in subgroups. Therefore we examined predictions of biochemical associations with the major symptom clusters, measures of attention and response variability.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy

UniBE Contributor:

Schimmelmann, Benno Karl Edgar

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1744-9081

Publisher:

BioMed Central

Language:

English

Submitter:

Myriam Pyrlik

Date Deposited:

04 Oct 2013 14:11

Last Modified:

09 Dec 2014 00:48

Publisher DOI:

10.1186/1744-9081-6-32

PubMed ID:

20534153

Web of Science ID:

000279703100001

BORIS DOI:

10.7892/boris.1706

URI:

https://boris.unibe.ch/id/eprint/1706 (FactScience: 203636)

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