Bruegger, Dominik; Koth, Anna-Lucia; Dysli, Muriel; Goldblum, David; Abegg, Mathias; Tschopp, Markus; Tappeiner, Christoph (2022). Evaluation of the Reddesa Chart, a New Red Desaturation Testing Method, for Optic Neuritis Screening and Grading in Clinical Routine. Frontiers in neurology, 13(898064), p. 898064. Frontiers Media S.A. 10.3389/fneur.2022.898064
|
Text
fneur-13-898064.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
Background
Optic neuritis usually leads to reduced color sensitivity. Most often, the change of red color, the so-called red desaturation, is tested in clinical routine. The aim of this study was to test the feasibility of the Reddesa chart, a new red desaturation test based on polarization, as a screening method for optic neuropathy.
Methods
A total of 20 patients with unilateral optic neuritis and 20 healthy controls were included in this prospective pilot study. Ophthalmological examination included assessment of best corrected visual acuity (BCVA), slit lamp examination, fundoscopy, testing of relative afferent pupillary defect (RAPD) and red desaturation with the red cup test and the Reddesa chart.
Results
The mean BCVA in the optic neuritis group was 0.76 ± 0.36 in the affected eye (95% of eyes with RAPD, 75% of eyes with difference in the Reddesa test) and 1.28 ± 0.24 in the healthy eye, whereas in the control group, BCVA was 1.14 ± 0.11 in the right eye and 1.15 ± 0.14 in the left eye (none of the eyes with RAPD or abnormal Reddesa test). In our study, the Reddesa test showed a positive predictive value of 100% and a negative predictive value of 80% for detecting optic neuritis.
Conclusion
The Reddesa chart allows to quantify red desaturation and has the potential to be implemented as a screening test in clinical routine.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Brügger, Dominik Marcel, Dysli, Denise-Muriel, Abegg, Mathias, Tschopp, Markus, Tappeiner, Christoph |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1664-2295 |
Publisher: |
Frontiers Media S.A. |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
27 Jul 2022 11:27 |
Last Modified: |
05 Dec 2022 16:22 |
Publisher DOI: |
10.3389/fneur.2022.898064 |
PubMed ID: |
35873783 |
Uncontrolled Keywords: |
Reddesa chart optic neuritis red cap test red desaturation screening |
BORIS DOI: |
10.48350/171539 |
URI: |
https://boris.unibe.ch/id/eprint/171539 |
Actions (login required)
 |
Edit item |