Sarnthein, Johannes; Seidel, Kathleen; Neidert, Marian Christoph; Raabe, Andreas; Sala, Francesco; Tonn, Joerg Christian; Thon, Niklas; Szelenyi, Andrea (2022). Evaluation of a new cortical strip electrode for intraoperative somatosensory monitoring during perirolandic brain surgery. Clinical neurophysiology, 142, pp. 44-51. Elsevier 10.1016/j.clinph.2022.07.497
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OBJECTIVE
During neurosurgical procedures, strip electrodes should have low impedance and sufficient adherence on the brain surface. We evaluated the signal quality, safety, and performance of a novel strip electrode (WISE Cortical Strip, WCS®), with conductive electrode contacts created with platinum nanoparticles embedded in a polymer base.
METHODS
In a multicenter interventional, non-inferiority study, we compared WCS to a conventional strip electrode (Ad-Tech). We recorded impedance and somatosensory evoked potentials (SEP) and determined the signal-to-noise ratio (SNR). We performed direct stimulation of the motor cortex. An external clinical event committee rated safety and adverse events and users rated usability.
RESULTS
During 32 brain surgeries in the paracentral region, WCS was rated safe and effective in signal transmission. Two seizure events were classified as probably related to the stimulation with WCS. The users rated WCS adhesion to the brain as satisfactory but reported difficulties sliding the WCS under the dura. The median (IQR) impedance of WCS was lower than for Ad-Tech: 2.7 (2.3-3.7) vs 5.30 (4.3-6.6) kΩ (p < 0.005). The SNR of SEP was non-inferior for WCS compared to Ad-Tech.
CONCLUSIONS
The impedance of WCS was lower than Ad-Tech without safety limitations. In small craniotomies not exposing the motor cortex its use may be limited.
SIGNIFICANCE
Low impedance electrodes facilitate recordings with high SNR.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery |
UniBE Contributor: |
Seidel, Kathleen, Raabe, Andreas |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1872-8952 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
16 Aug 2022 15:31 |
Last Modified: |
05 Dec 2022 16:22 |
Publisher DOI: |
10.1016/j.clinph.2022.07.497 |
PubMed ID: |
35964495 |
Uncontrolled Keywords: |
Direct cortical stimulation Electrocorticography Motor evoked potentials Somatosensory evoked potentials Strip electrode |
BORIS DOI: |
10.48350/172050 |
URI: |
https://boris.unibe.ch/id/eprint/172050 |
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