Jesse, Christopher Marvin; Alvarez Abut, Pablo; Wermelinger, Jonathan; Raabe, Andreas; Schär, Ralph T; Seidel, Kathleen (2022). Functional Outcome in Spinal Meningioma Surgery and Use of Intraoperative Neurophysiological Monitoring. Cancers, 14(16) MDPI AG 10.3390/cancers14163989
|
Text
cancers-14-03989.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
Data on intraoperative neurophysiological monitoring (IOM) during spinal meningioma (SM) surgery are scarce. The aim of this study was to assess the role of IOM and its impact on post-operative functional outcome. Eighty-six consecutive surgically treated SM patients were included. We assessed pre and post-operative Modified McCormick Scale (mMCS), radiological and histopathological data and IOM findings. Degree of cord compression was associated with preoperative mMCS and existence of motor or sensory deficits (p < 0.001). IOM was used in 51 (59.3%) patients (IOM-group). Median pre and post-operative mMCS was II and I, respectively (p < 0.001). Fifty-seven (66.3%) patients showed an improvement of at least one grade in the mMCS one year after surgery. In the IOM group, only one patient had worsened neurological status, and this was correctly predicted by alterations in evoked potentials. Analysis of both groups found no significantly better neurological outcome in the IOM group, but IOM led to changes in surgical strategy in complex cases. Resection of SM is safe and leads to improved neurological outcome in most cases. Both complication and tumor recurrence rates were low. We recommend the use of IOM in surgically challenging cases, such as completely ossified or large ventrolateral SM.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery |
UniBE Contributor: |
Jesse, Christopher Marvin, Alvarez Abut, Pablo Abel, Wermelinger, Jonathan, Raabe, Andreas, Schär, Ralph Thomas, Seidel, Kathleen |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2072-6694 |
Publisher: |
MDPI AG |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
29 Aug 2022 14:32 |
Last Modified: |
05 Dec 2022 16:23 |
Publisher DOI: |
10.3390/cancers14163989 |
PubMed ID: |
36010979 |
Uncontrolled Keywords: |
IDEM McCormick scale functional outcome intraoperative neurophysiological monitoring meningioma spinal meningioma |
BORIS DOI: |
10.48350/172422 |
URI: |
https://boris.unibe.ch/id/eprint/172422 |
Actions (login required)
 |
Edit item |