Hakim, Arsany; Hool, Sara-Lynn; Yassa, Nabil; Breiding, Philipe Sebastian; Pastore-Wapp, Manuela; Caversaccio, Marco; Anschuetz, Lukas; Wagner, Franca (2022). Signal Alteration of the Inner Ear on High-Resolution Three-Dimensional Constructive Interference in Steady State Sequence in Patients with Ménière's Disease and Labyrinthitis. Audiology & neuro-otology, 27(6), pp. 449-457. Karger 10.1159/000525419
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INTRODUCTION
The aim of this study is to evaluate signal alteration in the inner ear using three-dimensional (3D)-constructive interference in steady state (CISS) sequence in patients with Ménière's disease and labyrinthitis and its correlation with clinical and audiological parameters.
METHODS
The medical records of the department of otorhinolaryngology were searched for patients with Ménière's disease or labyrinthitis who underwent MRI with 3D-CISS sequence. Blinded analysis of these patients and of MRI from control subjects without middle or inner ear symptoms was performed to detect any signal asymmetry of the inner ear structures. The results were correlated with clinical symptoms and results of audiological and vestibular tests.
RESULTS
Fifty-eight patients with definite Ménière's disease and 5 patients with labyrinthitis as well as 41 control exams were included. A separate analysis was performed for patients with probable Ménière's disease (n = 68). A total of 172 3D-CISS sequences were analyzed by 2 blinded independent neuroradiologists. A CISS-hypointense signal of the inner ear structures was found in 3 patients with definite Ménière's disease (5.2%), in 4 patients with probable Ménière's disease (5.9%), and 2 patients with labyrinthitis (40%). No CISS hypointensity was found in the control group. Although no significant difference in symptoms or audiological test results was found between patients with and without this signal change, the side of hypointensity was frequently correlated with the symptomatic side and with hearing impairment.
DISCUSSION/CONCLUSION
CISS hypointensity of the inner ear structures was evident in patients with clinical conditions other than vestibular schwannoma - more frequently in labyrinthitis than in Ménière's disease. This signal alteration was frequently encountered on the same symptomatic side as that of the pathological audiology tests, but it is not a predictor for hearing or vestibular impairment.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT) |
UniBE Contributor: |
Hakim, Arsany, Hool, Sara-Lynn, Breiding, Philipe Sebastian, Pastore-Wapp, Manuela, Caversaccio, Marco, Anschütz, Lukas Peter, Wagner, Franca |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1420-3030 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
31 Aug 2022 10:00 |
Last Modified: |
05 Dec 2022 16:23 |
Publisher DOI: |
10.1159/000525419 |
PubMed ID: |
36037798 |
Uncontrolled Keywords: |
Cochlea Constructive interference in steady state Endolymphatic hydrops Inner ear MRI |
BORIS DOI: |
10.48350/172476 |
URI: |
https://boris.unibe.ch/id/eprint/172476 |
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