Enz, Tim J; Maloca, Peter M; Tschopp, Markus; Menke, Marcel N; Tribble, James R; Williams, Pete A; Inglin, Nadja; Steitz, Ulrike; Scholl, Hendrik P N; Papazoglou, Anthia (2022). Volume-rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring. Journal of biophotonics, 15(12), e202200169. Wiley-VCH 10.1002/jbio.202200169
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Journal_of_Biophotonics_-_2022_-_Enz_-_Volume_rendered_optical_coherence_tomography_angiography_during_ocular_interventions-1.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (2MB) | Preview |
We aimed to test for feasibility of volume-rendered optical coherence tomography angiography (OCTA) as a novel method for assessing/quantifying retinal vasculature during ocular procedures and to explore the potential for intraoperative use. Thirty patients undergoing periocular anaesthesia were enrolled, since published evidence suggests a reduction in ocular blood flow. Retinal perfusion was monitored based on planar OCTA image-derived data provided by a standard quantification algorithm and postprocessed/volume-rendered OCTA data using a custom software script. Overall, imaging procedures were successful, yet imaging artifacts occurred frequently. In interventional eyes, perfusion parameters decreased during anaesthesia. Planar image-derived and volume rendering-derived parameters were correlated. No correlation was found between perfusion parameters and a motion artifact score developed for this study, yet all perfusion parameters correlated with signal strength as displayed by the device. Concluding, volume-rendered OCTA allows for noninvasive three-dimensional retinal vasculature assessment/quantification in challenging surgical settings and appears generally feasible for intraoperative use.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Tschopp, Markus, Menke, Marcel |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1864-063X |
Publisher: |
Wiley-VCH |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
15 Sep 2022 08:01 |
Last Modified: |
23 Dec 2022 00:13 |
Publisher DOI: |
10.1002/jbio.202200169 |
PubMed ID: |
36089335 |
Uncontrolled Keywords: |
3D vasculature reconstruction intraoperative retinal perfusion monitoring retinal vessel size volume-rendered optical coherence tomography angiography |
BORIS DOI: |
10.48350/172873 |
URI: |
https://boris.unibe.ch/id/eprint/172873 |
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