Volume-rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring.

Enz, Tim J; Maloca, Peter M; Tschopp, Markus; Menke, Marcel N; Tribble, James R; Williams, Pete A; Inglin, Nadja; Steitz, Ulrike; Scholl, Hendrik P N; Papazoglou, Anthia (2022). Volume-rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring. Journal of biophotonics, 15(12), e202200169. Wiley-VCH 10.1002/jbio.202200169

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We aimed to test for feasibility of volume-rendered optical coherence tomography angiography (OCTA) as a novel method for assessing/quantifying retinal vasculature during ocular procedures and to explore the potential for intraoperative use. Thirty patients undergoing periocular anaesthesia were enrolled, since published evidence suggests a reduction in ocular blood flow. Retinal perfusion was monitored based on planar OCTA image-derived data provided by a standard quantification algorithm and postprocessed/volume-rendered OCTA data using a custom software script. Overall, imaging procedures were successful, yet imaging artifacts occurred frequently. In interventional eyes, perfusion parameters decreased during anaesthesia. Planar image-derived and volume rendering-derived parameters were correlated. No correlation was found between perfusion parameters and a motion artifact score developed for this study, yet all perfusion parameters correlated with signal strength as displayed by the device. Concluding, volume-rendered OCTA allows for noninvasive three-dimensional retinal vasculature assessment/quantification in challenging surgical settings and appears generally feasible for intraoperative use.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Tschopp, Markus, Menke, Marcel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1864-063X

Publisher:

Wiley-VCH

Language:

English

Submitter:

Pubmed Import

Date Deposited:

15 Sep 2022 08:01

Last Modified:

23 Dec 2022 00:13

Publisher DOI:

10.1002/jbio.202200169

PubMed ID:

36089335

Uncontrolled Keywords:

3D vasculature reconstruction intraoperative retinal perfusion monitoring retinal vessel size volume-rendered optical coherence tomography angiography

BORIS DOI:

10.48350/172873

URI:

https://boris.unibe.ch/id/eprint/172873

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