Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells.

Griffiths, Gillian M; Mueller, Christoph (1991). Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells. Immunology today, 12(11), pp. 415-419. Elsevier 10.1016/0167-5699(91)90145-J

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Perforin and granzymes are considered to be instrumental in cell-mediated cytolysis by cytotoxic T cells and natural killer cells. Here, Gillian Griffiths and Christoph Mueller describe the expression of perforin and granzymes, emphasizing studies in vivo, and discuss the possibility that these proteins are useful diagnostic markers for immune responses involving cytolytic cells.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Müller, Christoph

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0167-5699

Publisher:

Elsevier

Language:

English

Submitter:

Christoph Müller

Date Deposited:

22 Sep 2022 15:13

Last Modified:

22 Sep 2022 15:13

Publisher DOI:

10.1016/0167-5699(91)90145-J

PubMed ID:

1786074

URI:

https://boris.unibe.ch/id/eprint/172935

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