Natural course of visual snow syndrome: a long-term follow-up study.

Graber, Michael; Scutelnic, Adrian; Klein, Antonia; Puledda, Francesca; Goadsby, Peter J; Schankin, Christoph J (2022). Natural course of visual snow syndrome: a long-term follow-up study. Brain Communications, 4(5), pp. 1-6. Oxford University Press 10.1093/braincomms/fcac230

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Visual snow syndrome is characterized by a continuous visual disturbance resembling a badly tuned analogue television and additional visual and non-visual symptoms causing significant disability. The natural course of visual snow syndrome has not hitherto been studied. In this prospective longitudinal study, 78 patients with the diagnosis of visual snow syndrome made in 2011 were re-contacted in 2019 to assess symptom evolution using a semi-structured questionnaire. Forty patients (51% of 78) were interviewed after 84 ± 5 months (mean ± SD). In all patients, symptoms had persisted. Visual snow itself was less frequently rated as the most disturbing symptom (72 versus 42%, P = 0.007), whereas a higher proportion of patients suffered primarily from entopic phenomena (2 versus 17%, P = 0.024). New treatment was commenced in 14 (35%) patients, of whom in seven, visual snow syndrome was ameliorated somewhat. Three (7%) experienced new visual migraine aura without headache, and one (2%) had new migraine headache. There were no differences in the levels of anxiety and depression measured by the Patient Health Questionnaire 8 and the Generalized Anxiety Disorder Scale 7. Thirty-eight patients (49%) were lost to follow-up. In visual snow syndrome, symptoms can persist over 8 years without spontaneous resolution, although visual snow itself might become less bothersome.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Graber, Michael (B), Scutelnic, Adrian, Klein, Antonia, Schankin, Christoph Josef

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2632-1297

Publisher:

Oxford University Press

Language:

English

Submitter:

Pubmed Import

Date Deposited:

26 Sep 2022 14:07

Last Modified:

29 Mar 2023 23:38

Publisher DOI:

10.1093/braincomms/fcac230

PubMed ID:

36147453

Uncontrolled Keywords:

aura follow-up migraine natural course visual snow

BORIS DOI:

10.48350/173227

URI:

https://boris.unibe.ch/id/eprint/173227

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