Lucchese, Alberta; Di Stasio, Dario; Romano, Antonio; Fiori, Fausto; De Felice, Guido Paolo; Lajolo, Carlo; Serpico, Rosario; Cecchetti, Francesco; Petruzzi, Massimo (2022). Correlation between Oral Lichen Planus and Viral Infections Other Than HCV: A Systematic Review. Journal of clinical medicine, 11(18) MDPI 10.3390/jcm11185487
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OBJECTIVES
This review aimed to evaluate the correlation between viral infections (HPV, EBV, HSV-1, CMV) other than HCV and oral lichen planus to assess if there is sufficient evidence to establish if these viruses can play a role in the etiopathogenesis of the disease.
MATERIALS AND METHODS
We reviewed the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library), employing MeSH terms such as "oral lichen planus" and "OLP" in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria.
RESULTS
A total of 43 articles of the 1219 results initially screened were included in the study. We allocated the 43 selected items into four groups, according to each related virus: HPV, EBV, HSV-1, and CMV.
CONCLUSIONS
Heterogeneous results neither confirm nor exclude a direct correlation between the investigated viral infections and oral lichen planus etiopathogenesis and its feasible malignant transformation. Many viral agents can cause oral lesions and act as cancerizing agents. Future studies could be desirable to produce comparable statistical analyses and enhance the quantity and quality of the outcomes to promote the translation of research into clinical practice.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2077-0383 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
26 Sep 2022 13:31 |
Last Modified: |
27 Sep 2022 05:54 |
Publisher DOI: |
10.3390/jcm11185487 |
PubMed ID: |
36143134 |
Uncontrolled Keywords: |
CMV EBV HPV HSV-1 oral cancer oral lichen planus |
BORIS DOI: |
10.48350/173237 |
URI: |
https://boris.unibe.ch/id/eprint/173237 |
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