Lunger, Lukas; Melmer, Andreas; Sturm, Wolfgang; Lamina, Claudia; Tschoner, Alexander; Engl, Julia; Hönlinger, Armin; Engler, Clemens; Willeit, Peter; Kiechl, Stefan; Willeit, Johann; Öfner, Dietmar; Wykypiel, Heinz; Laimer, Markus; Tilg, Herbert; Ebenbichler, Christoph (2023). Bariatric surgery prevents carotid wall thickness progression. Wiener klinische Wochenschrift, 135(5-6), pp. 151-157. Springer-Verlag 10.1007/s00508-022-02090-3
|
Text
s00508-022-02090-3.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (368kB) | Preview |
BACKGROUND
Bariatric surgery is a treatment option for patients with severe obesity and improves parameters of cardiovascular and/or metabolic disease. Carotid intima media thickness (C-IMT) is a surrogate measure of subclinical atherosclerosis. Previous studies showed short to mid-term arrest and even regression of C‑IMT progression following bariatric surgery. We aimed to investigate the long-term effect of weight loss on C‑IMT progression 10 years after bariatric surgery in comparison to a population-based control cohort.
METHODS
In total, 21 eligible patients were examined preoperatively, at 5 and 10 years after bariatric surgery. Anthropometric parameters, plasma triglycerides, total cholesterol, high-density lipoprotein cholesterol (HDL-C), insulin, and glucose were assessed at all three study visits. C‑IMT was measured via B‑mode scans of the common carotid artery. C‑IMT progression was measured in an age-matched and BMI-matched cohort selected from the population-based Bruneck study to compare with changes in C‑IMT progression after bariatric surgery.
RESULTS
C‑IMT remained stable over the 10-year observation period after bariatric surgery. The control cohort showed a significant C‑IMT progression over 10 years. The difference in C‑IMT progression over 10 years was significant (p < 0.01) between both cohorts.
CONCLUSION
Weight loss induced by bariatric surgery halts the natural progression of C‑IMT over a 10-year observation period.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition |
UniBE Contributor: |
Melmer, Andreas, Laimer, Markus |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0043-5325 |
Publisher: |
Springer-Verlag |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
10 Oct 2022 10:10 |
Last Modified: |
18 Mar 2023 00:12 |
Publisher DOI: |
10.1007/s00508-022-02090-3 |
PubMed ID: |
36205799 |
Uncontrolled Keywords: |
Bariatric surgery Carotid intima-media thickness Carotid wall thickness progression Subclinical atherosclerosis Weight loss |
BORIS DOI: |
10.48350/173590 |
URI: |
https://boris.unibe.ch/id/eprint/173590 |
Actions (login required)
 |
Edit item |