Zaffarano, Luciano; Salerno, Claudia; Campus, Guglielmo; Cirio, Silvia; Balian, Araxi; Karanxha, Lorena; Cagetti, Maria Grazia (2022). Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis. International journal of environmental research and public health, 19(19) MDPI 10.3390/ijerph191912917
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A systematic review and meta-analysis were carried out to evaluate the efficacy of silver diamine fluoride (SDF) in controlling caries progression in cavitated primary molars. A search for randomized and non-randomized trials with follow-up > 6 months was performed using PubMed, Scopus and Embase. The Cochrane risk of bias tools were used for the quality assessment. The success rate and odds ratios were chosen to calculate the effect size for the meta-analysis. A total of 792 papers were identified and 9 were selected. A high variability regarding SDF application protocol was found; otherwise, caries arrest was always recorded using visual/tactile methods. Two studies were judged at low risk of bias, six at moderate risk and one at high risk. Data from five studies were aggregated for meta-analysis. Heterogeneity was found moderate (I2 = 35.69%, p = 0.18). SDF application was found to be overall effective (fixed effect model) in arresting caries progression (ES = 0.35, p < 0.01). In a total of 622 arrested lesions, out of 1205 considered, the caries arrest rate was 51.62% ± 27.40% (Confidence = 1.55) using SDF ≥ 38% applied annually or biannually. In conclusion, when applied to active cavitated caries lesions in primary molars, SDF appears to be effective in arresting dental caries progression, especially if applied biannually.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry |
UniBE Contributor: |
Campus, Guglielmo Giuseppe |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1660-4601 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
17 Oct 2022 12:40 |
Last Modified: |
14 May 2023 23:43 |
Publisher DOI: |
10.3390/ijerph191912917 |
PubMed ID: |
36232217 |
Uncontrolled Keywords: |
SDF dental caries minimally invasive treatment non-invasive treatment primary teeth silver diamine fluoride |
BORIS DOI: |
10.48350/173773 |
URI: |
https://boris.unibe.ch/id/eprint/173773 |
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