Five-year results following regenerative periodontal surgery with an enamel matrix derivative in patients with different smoking status.

De Ry, Siro Pietro; Pagnamenta, Marco; Ramseier, Christoph Andreas; Roccuzzo, Andrea; Salvi, Giovanni Edoardo; Sculean, Anton (2022). Five-year results following regenerative periodontal surgery with an enamel matrix derivative in patients with different smoking status. Quintessence international, 53(10), pp. 832-838. Quintessenz 10.3290/j.qi.b3418233

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OBJECTIVE

To evaluate the five-year results following regenerative periodontal surgery of intrabony defects using an enamel matrix derivative (EMD) in patients with different smoking status.

METHOD AND MATERIALS

The dental records of patients treated with regenerative periodontal surgery with EMD between 2001 and 2011 were screened. The clinical parameters at baseline (T0) and 6 months (T1) and 5 years (T2) after surgery were collected and analyzed in relation to patient's smoking status (smokers, former smokers, and nonsmokers).

RESULTS

A total of 71 sites were initially assessed in 38 patients. In total, 56 sites could be evaluated at T1, and 34 after 5 years (T2). At 6 months after surgery, a statistically significant mean probing pocket depth (PPD) reduction of 2.91 ± 1.60 mm and a mean clinical attachment level (CAL) gain of 1.89 ± 1.90 mm were measured. Nonsmokers revealed a greater, statistically not significant CAL gain compared to smokers (2.38 ± 2.12 mm vs 1.50 ± 1.71 mm). Although at 5 years the site-specific PPD values remained stable in nonsmokers, smokers showed an increase of 1.60 ± 2.41 mm.

CONCLUSIONS

The present study provides evidence that regenerative periodontal surgery with EMD may lead to clinically relevant improvements even in smoking patients. However, the positive effect of EMD seems to be limited in time and can only partially compensate for the negative influence of smoking.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology

UniBE Contributor:

De Ry, Siro Pietro Lorenzo, Ramseier, Christoph Andreas, Roccuzzo, Andrea, Salvi, Giovanni Edoardo, Sculean, Anton

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1936-7163

Publisher:

Quintessenz

Language:

English

Submitter:

Beatrix Margrit Stalder

Date Deposited:

05 Dec 2022 08:10

Last Modified:

17 Jan 2023 13:28

Publisher DOI:

10.3290/j.qi.b3418233

PubMed ID:

36169272

Uncontrolled Keywords:

enamel matrix derivative (EMD) intrabony defects long-term results periodontal regeneration regenerative periodontal surgery smoking

BORIS DOI:

10.48350/174284

URI:

https://boris.unibe.ch/id/eprint/174284

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