Ongoing toxin-positive diphtheria outbreaks in a federal asylum centre in Switzerland, analysis July to September 2022.

Kofler, Jacob; Ramette, Alban; Iseli, Patricia; Stauber, Lea; Fichtner, Jens; Droz, Sara; Zihler Berner, Annina; Meier, Anna Bettina; Begert, Michelle; Negri, Sabine; Jachmann, Anne; Keller, Peter Michael; Staehelin, Cornelia; Grützmacher, Barbara (2022). Ongoing toxin-positive diphtheria outbreaks in a federal asylum centre in Switzerland, analysis July to September 2022. Eurosurveillance, 27(44) European Centre for Disease Prevention and Control 10.2807/1560-7917.ES.2022.27.44.2200811

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Two diphtheria outbreaks occurred in a Swiss asylum center from July to October 2022, one is still ongoing. Outbreaks mainly involved minors and included six symptomatic respiratory diphtheria cases requiring antitoxin. Phylogenomic analyses showed evidence of imported and local transmissions of toxigenic strains in respiratory and skin lesion samples. Given the number of cases (n = 20) and the large genetic diversity accumulating in one centre, increased awareness and changes in public health measures are required to prevent and control diphtheria outbreaks.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Clinical Microbiology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > General Bacteriology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases

UniBE Contributor:

Ramette, Alban Nicolas, Stauber, Lea, Droz, Sara Christine, Zihler, Annina, Keller, Peter Michael, Staehelin, Cornelia

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1560-7917

Publisher:

European Centre for Disease Prevention and Control

Language:

English

Submitter:

Pubmed Import

Date Deposited:

09 Nov 2022 11:02

Last Modified:

05 Dec 2022 16:27

Publisher DOI:

10.2807/1560-7917.ES.2022.27.44.2200811

PubMed ID:

36330823

Uncontrolled Keywords:

Corynebacterium diphtheriae diphtheria epidemiology public health, genomic sequencing

BORIS DOI:

10.48350/174520

URI:

https://boris.unibe.ch/id/eprint/174520

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