Small RNA-mediated genome rearrangement pathways in ciliates.

Gao, Yunyi; Solberg, Therese; Wang, Chundi; Gao, Feng (2023). Small RNA-mediated genome rearrangement pathways in ciliates. Trends in genetics, 39(2), pp. 94-97. Elsevier Current Trends 10.1016/j.tig.2022.10.001

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Most eukaryotes employ a combination of transcriptional and post-transcriptional silencing mechanisms to suppress transposons, yet ciliates employ a more extreme approach. They separate germline and somatic functions into distinct nuclei, enabling the elimination of transposons from the active somatic genome through diverse small RNA-mediated genome rearrangement pathways during sexual processes.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Solberg, Therese

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

0168-9525

Publisher:

Elsevier Current Trends

Language:

English

Submitter:

Pubmed Import

Date Deposited:

16 Nov 2022 07:39

Last Modified:

26 Jan 2023 00:14

Publisher DOI:

10.1016/j.tig.2022.10.001

PubMed ID:

36371355

Uncontrolled Keywords:

DNA elimination ciliate genome rearrangement nuclear dimorphism small RNA transposons

BORIS DOI:

10.48350/174742

URI:

https://boris.unibe.ch/id/eprint/174742

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