Work-Related Factors and Lung Cancer Survival: A Population-Based Study in Switzerland (1990-2014).

Bovio, Nicolas; Grzebyk, Michel; Arveux, Patrick; Bulliard, Jean-Luc; Chiolero, Arnaud; Fournier, Evelyne; Germann, Simon; Konzelmann, Isabelle; Maspoli, Manuela; Rapiti, Elisabetta; Guseva Canu, Irina (2022). Work-Related Factors and Lung Cancer Survival: A Population-Based Study in Switzerland (1990-2014). International journal of environmental research and public health, 19(21), p. 13856. MDPI 10.3390/ijerph192113856

Preview

Text ijerph-19-13856.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (984kB) | Preview

While previous Swiss studies have demonstrated differences in lung cancer mortality between occupational groups, no estimates are available on the association of occupation-related factors with lung cancer survival. This study aimed at determining whether occupation or work-related factors after diagnosis affect lung cancer survival. We used cancer registry records to identify lung cancer patients diagnosed between 1990 and 2014 in western Switzerland (n = 5773) matched with the Swiss National Cohort. The effect of occupation, the skill level required for the occupation, and the socio-professional category on 5-year lung cancer survival was assessed using non-parametric and parametric methods, controlling for histological type and tumour stage. We found that the net survival varied across skill levels and that the lowest skill level was associated with worse survival in both men and women. In the parametric models with minimal adjustment, we identified several occupational groups at higher risk of mortality compared to the reference category, particularly among men. After adjustment for histological type of lung cancer and tumour stage at diagnosis, most hazard ratios remained higher than 1, though non-statistically significant. Compared to top managers and self-employed workers, workers in paid employment without specific information on occupation were identified as the most at-risk socio-professional category in nearly all models. As this study was conducted using a relatively small sample and limited set of covariates, further studies are required, taking into account smoking habits and administrated cancer treatments. Information on return to work and working conditions before and after lung cancer diagnosis will also be highly valuable for analysing their effect on net lung cancer survival in large nationwide or international studies. Such studies are essential for informing health and social protection systems, which should guarantee appropriate work conditions for cancer survivors, beneficial for their quality of life and survival.

Interest & Impact

Downloads

17 since deposited on 16 Nov 2022
17 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item