Successful pregnancy in a cystic fibrosis patient with a severe impairment of lung function receiving Elexacaftor-Tezacaftor-Ivacaftor [case report].

Balmpouzis, Zisis; Faure van Rossum, Annabelle; Baud, David; Panchaud, Alice; Mitropoulou, Georgia; Mazza Stalder, Jesica; Koutsokera, Angela (2022). Successful pregnancy in a cystic fibrosis patient with a severe impairment of lung function receiving Elexacaftor-Tezacaftor-Ivacaftor [case report]. Respiratory Medicine Case Reports, 40, p. 101776. Elsevier 10.1016/j.rmcr.2022.101776

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Before the arrival of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulators women with CF and impaired lung function were experiencing a high risk of complications and mortality during and the years after pregnancy. The arrival of the highly efficient CFTR modulator, Elexacaftor-Tezacaftor-Ivacaftor (ETI) resulted in an improvement of lung function, quality of life and fertility. Here we report a case of successful pregnancy and uncomplicated delivery for a CF patient with severely impaired lung function receiving ETI prior to conception.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Panchaud Monnat, Alice Elke Martine

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2213-0071

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

23 Nov 2022 12:15

Last Modified:

05 Dec 2022 16:28

Publisher DOI:

10.1016/j.rmcr.2022.101776

PubMed ID:

36386288

Uncontrolled Keywords:

Cystic fibrosis Elexacaftor-Tezacaftor-Ivacaftor Impaired lung function Pregnancy

BORIS DOI:

10.48350/174881

URI:

https://boris.unibe.ch/id/eprint/174881

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