Risk and protective factors for self-harm and suicide in children and adolescents: a systematic review and meta-analysis protocol.

Farbstein, Dan; Lukito, Steve; Yorke, Isabel; Wilson, Emma; Crudgington, Holly; El-Aalem, Omar; Cliffe, Charlotte; Bergou, Nicol; Itani, Lynn; Owusu, Andy; Sedgwick, Rosemary; Singh, Nidhita; Tarasenko, Anna; Tucker, Gavin; Woodhouse, Emma; Suzuki, Mimi; Myerscough, Anna Louise; Lopez Chemas, Natalia; Abdel-Halim, Nadia; Del Giovane, Cinzia; ... (2022). Risk and protective factors for self-harm and suicide in children and adolescents: a systematic review and meta-analysis protocol. BMJ open, 12(11), e058297. BMJ Publishing Group 10.1136/bmjopen-2021-058297

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INTRODUCTION

Self-harm and suicide are major public health concerns among children and adolescents. Many risk and protective factors for suicide and self-harm have been identified and reported in the literature. However, the capacity of these identified risk and protective factors to guide assessment and management is limited due to their great number. This protocol describes an ongoing systematic review and meta-analysis which aims to examine longitudinal studies of risk factors for self-harm and suicide in children and adolescents, to provide a comparison of the strengths of association of the various risk factors for self-harm and suicide and to shed light on those that require further investigation.

METHODS AND ANALYSIS

We perform a systematic search of the literature using the databases EMBASE, PsycINFO, Medline, CINAHL and HMIC from inception up to 28 October 2020, and the search will be updated before the systematic review publication. Additionally, we will contact experts in the field, including principal investigators whose peer-reviewed publications are included in our systematic review as well as investigators from our extensive research network, and we will search the reference lists of relevant reviews to retrieve any articles that were not identified in our search. We will extract relevant data and present a narrative synthesis and combine the results in meta-analyses where there are sufficient data. We will assess the risk of bias for each study using the Newcastle-Ottawa Scale and present a summary of the quantity and the quality of the evidence for each risk or protective factor.

ETHICS AND DISSEMINATION

Ethical approval will not be sought as this is a systematic review of the literature. Results will be published in mental health journals and presented at conferences focused on suicide prevention.

PROSPERO REGISTRATION NUMBER

CRD42021228212.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Del Giovane, Cinzia

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2044-6055

Publisher:

BMJ Publishing Group

Language:

English

Submitter:

Pubmed Import

Date Deposited:

28 Nov 2022 09:58

Last Modified:

05 Dec 2022 16:29

Publisher DOI:

10.1136/bmjopen-2021-058297

PubMed ID:

36428021

Uncontrolled Keywords:

child & adolescent psychiatry community child health suicide & self-harm

BORIS DOI:

10.48350/175180

URI:

https://boris.unibe.ch/id/eprint/175180

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