Maternal and fetal cord blood lipids in intrauterine growth restriction

Pecks, Ulrich; Brieger, Meike; Schiessl, Barbara; Bauerschlag, Dirk O; Piroth, Daniela; Bruno, Benjamin; Fitzner, Christina; Orlikowsky, Thorsten; Maass, Nicolai; Rath, Werner (2012). Maternal and fetal cord blood lipids in intrauterine growth restriction. Journal of perinatal medicine, 40(3), pp. 287-96. Berlin: De Gruyter 10.1515/JPM.2011.135

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Small for gestational age neonates (SGA) could be subdivided into two groups according to the underlying causes leading to low birth weight. Intrauterine growth restriction (IUGR) is a pathologic condition with diminished growth velocity and fetal compromised well-being, while non-growth restricted SGA neonates are constitutionally (genetically determined) small. Antenatal sonographic measurements are used to differentiate these two subgroups. Maternal metabolic changes contribute to the pathogenesis of IUGR. A disturbed lipid metabolism and cholesterol supply might affect the fetus, with consequences for fetal programming of cardiovascular diseases. We evaluated fetal serum lipids and hypothesized a more atherogenic lipoprotein profile in IUGR fetuses.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension

UniBE Contributor:

Pecks, Ulrich

ISSN:

0300-5577

Publisher:

De Gruyter

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:42

Last Modified:

05 Dec 2022 14:13

Publisher DOI:

10.1515/JPM.2011.135

PubMed ID:

22505508

Web of Science ID:

000303977800014

URI:

https://boris.unibe.ch/id/eprint/17523 (FactScience: 225305)

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