Fungal hyphae regulate bacterial diversity and plasmid-mediated functional novelty during range expansion.

Ruan, Chujin; Ramoneda, Josep; Gogia, Guram; Wang, Gang; Johnson, David R (2022). Fungal hyphae regulate bacterial diversity and plasmid-mediated functional novelty during range expansion. Current biology, 32(24), 5285-5294.e4. Cell Press 10.1016/j.cub.2022.11.009

[img] Text
1-s2.0-S0960982222017651-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (3MB)
[img]
Preview
Text
CURRENT-BIOLOGY-D-22-01013_R2.pdf - Accepted Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (12MB) | Preview

The amount of bacterial diversity present on many surfaces is enormous; however, how these levels of diversity persist in the face of the purifying processes that occur as bacterial communities expand across space (referred to here as range expansion) remains enigmatic. We shed light on this apparent paradox by providing mechanistic evidence for a strong role of fungal hyphae-mediated dispersal on regulating bacterial diversity during range expansion. Using pairs of fluorescently labeled bacterial strains and a hyphae-forming fungal strain that expand together across a nutrient-amended surface, we show that a hyphal network increases the spatial intermixing and extent of range expansion of the bacterial strains. This is true regardless of the type of interaction (competition or resource cross-feeding) imposed between the bacterial strains. We further show that the underlying cause is that flagellar motility drives bacterial dispersal along the hyphal network, which counteracts the purifying effects of ecological drift at the expansion frontier. We finally demonstrate that hyphae-mediated spatial intermixing increases the conjugation-mediated spread of plasmid-encoded antibiotic resistance. In conclusion, fungal hyphae are important regulators of bacterial diversity and promote plasmid-mediated functional novelty during range expansion in an interaction-independent manner.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE)

UniBE Contributor:

Johnson, David R.

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

1879-0445

Publisher:

Cell Press

Language:

English

Submitter:

Pubmed Import

Date Deposited:

05 Dec 2022 13:48

Last Modified:

21 Dec 2023 00:25

Publisher DOI:

10.1016/j.cub.2022.11.009

PubMed ID:

36455559

Uncontrolled Keywords:

antibiotic resistance bacterial diversity bacterial motility biofilms fungal hyphae horizontal gene transfer microbial dispersal plasmid conjugation range expansion

BORIS DOI:

10.48350/175424

URI:

https://boris.unibe.ch/id/eprint/175424

Actions (login required)

Edit item Edit item
Provide Feedback