Borgardts, Klara; Menzel-Severing, Johannes; Fischinger, Isaak; Geerling, Gerd; Seiler, Theo G (2023). Innovations in Corneal Crosslinking. Current eye research, 48(2), pp. 144-151. Informa Healthcare 10.1080/02713683.2022.2146725
Full text not available from this repository. (Request a copy)PURPOSE
Corneal Crosslinking (CXL) strengthens the keratoconus cornea and prevents further disease progression. Modified crosslinking protocols and different riboflavin solutions have been proposed to optimize the procedure and improve treatment success.
METHODS
PubMed research of relevant publications and report of own experiences with different CXL protocols.
RESULTS
Accelerated CXL shows comparable efficiency with shorter surgery time and similar complication rates. Customized CXL provides improved results with faster epithelial healing. CXL in a hyperoxic environment seems to be a safe and effective transepithelial alternative with presumably less complications and fewer side effects. Thin corneas (<400 µm) can be treated safely by corneal swelling using hypoosmolar riboflavin solutions and reducing the applied UV-energy. The combination of CXL with photorefractive keratectomy (PRK) can be considered in patients with contact lens intolerance improving visual acuity, however, with increased risk of visual loss compared to CXL alone. Two-Photon (2Ph) CXL is a promising new technology enabling three-dimensional CXL.
DISCUSSION
Recently developed CXL protocols offer advantages over the standard "Dresden-protocol" and should be considered in patients with progressive keratectasia.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Seiler, Günter Theodor Michael |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0271-3683 |
Publisher: |
Informa Healthcare |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
05 Dec 2022 09:58 |
Last Modified: |
08 Feb 2023 00:14 |
Publisher DOI: |
10.1080/02713683.2022.2146725 |
PubMed ID: |
36458595 |
Uncontrolled Keywords: |
CXL PRK customized oxygen riboflavin transepithelial |
URI: |
https://boris.unibe.ch/id/eprint/175461 |
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