Krebs, Fabian; Uhlmann, Katja; Stanga, Zeno; Kurmann, Silvia (2022). Distribution of oral nutritional supplements with medication: Is there a benefit? A systematic review. Nutrition, 96, p. 111569. Elsevier 10.1016/j.nut.2021.111569
|
Text
1-s2.0-S0899900721004317-main.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (579kB) | Preview |
OBJECTIVES
Disease-related malnutrition remains a major burden for patients and health care systems. The Medication Pass Nutritional Supplement Program (MEDPass) involves providing patients with oral nutritional supplements (ONS) in unusually small amounts three to four times per day during medication rounds. This systematic review aims to evaluate the impact of MEDPass ONS administration on compliance, total energy and protein intake, food intake, body weight and handgrip strength in hospitalized adults and nursing-home residents.
METHODS
We conducted a systematic literature search in the databases MEDLINE, Embase, ScienceDirect, and the Cochrane Library and included randomized controlled trials (RCTs), non-RCTs, and before-after studies. Validated tools specific to the study design were used to assess the included studies.
RESULTS
Ten studies were identified, including two RCTs, three non-RCTs, and five before-after trials. Compliance increased by 23.4% to 66% with MEDPass administration, resulting in compliance rates of 72.7% to 96%. With MEDPass administration, body weight increased by 1% to 6.8% or remained stable. The assessed evidence on total energy intake is ambiguous for protein, with a trend toward an increased intake. Trials on energy intake from food show mixed results as well. One study suggested a slight increase in handgrip strength. The included studies predominantly raise concerns for bias.
CONCLUSIONS
We conclude that MEDPass ONS administration increases compliance in hospitalized adults and nursing-home residents. For all other outcomes, robust and well-powered trials are necessary.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition |
UniBE Contributor: |
Stanga, Zeno |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0899-9007 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Laura Cavalli |
Date Deposited: |
13 Dec 2022 10:23 |
Last Modified: |
18 Dec 2022 02:06 |
Publisher DOI: |
10.1016/j.nut.2021.111569 |
PubMed ID: |
35074646 |
Uncontrolled Keywords: |
Body weight Compliance Energy MEDPass Oral nutritional supplements Protein handgrip strength |
BORIS DOI: |
10.48350/175777 |
URI: |
https://boris.unibe.ch/id/eprint/175777 |
Actions (login required)
 |
Edit item |