OsteoMacs and Their Role in Early Implant Failure and Osseointegration.

Yang, Richard M; Talib, Huzefa S; Miron, Richard J; Wiedemann, Thomas G (2022). OsteoMacs and Their Role in Early Implant Failure and Osseointegration. Compendium of continuing education in dentistry, 43(10), pp. 698-703. AEGIS Communications

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Dental implant failure cannot always be explained by clinical risk factors. Recent literature suggests that immune cells are pivotal players in the integration of biomaterials and have a co-relationship within a set of osteal macrophages known as "OsteoMacs." These cells have been known to polarize quickly between a M1 pro-inflammatory and a M2 wound healing state during implant osseointegration. OsteoMacs play a critical immune surveillance role in the osseointegration of dental implant healing and bone homeostasis. This review is intended to provide an overview of the current understanding of OsteoMacs and their role in early implant failure and osseointegration.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology

UniBE Contributor:

Miron, Richard John

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2158-1797

Publisher:

AEGIS Communications

Language:

English

Submitter:

Pubmed Import

Date Deposited:

20 Dec 2022 14:02

Last Modified:

20 Dec 2022 18:39

PubMed ID:

36516870

URI:

https://boris.unibe.ch/id/eprint/175927

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