Kruse, Christopher; Maier, Franziska; Spottke, Annika; Bach, Jan-Philipp; Bartels, Claudia; Buerger, Katharina; Fellgiebel, Andreas; Fliessbach, Klaus; Frölich, Lutz; Hausner, Lucrezia; Hellmich, Martin; Klöppel, Stefan; Klostermann, Arne; Kornhuber, Johannes; Laske, Christoph; Peters, Oliver; Priller, Josef; Richter-Schmidinger, Tanja; Schneider, Anja; Shah-Hosseini, Kija; ... (2023). Apathy in patients with Alzheimer's disease is a cost-driving factor. Alzheimer's & dementia, 19(7), pp. 2853-2864. Elsevier 10.1002/alz.12915
|
Text
Alzheimer_s_Dementia_-_2023_-_Kruse_-_Apathy_in_patients_with_Alzheimer_s_disease_is_a_cost_driving_factor..pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC). Download (436kB) | Preview |
BACKGROUND
Apathy is the most frequent neuropsychiatric symptom in patients with dementia of the Alzheimer's type (DAT). We analyzed the influence of apathy on the resource use of DAT patients and their caregivers.
METHODS
Included were baseline data of 107 DAT patients from a randomized clinical trial on apathy treatment. The Resource Utilization in Dementia (RUD) instrument assessed costs over a 1-month period prior to baseline. Cost predictors were determined via a least absolute shrinkage and selection operator (LASSO).
RESULTS
On average, total monthly costs were €3070, of which €2711 accounted for caregivers' and €359 for patients' costs. An increase of one point in the Apathy Evaluation Scale resulted in a 4.1% increase in total costs.
DISCUSSION
Apathy is a significant cost driving factor for total costs in mild to moderate DAT. Effective treatment of apathy might be associated with reduced overall costs in DAT.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Geriatric Psychiatry and Psychotherapy |
UniBE Contributor: |
Klöppel, Stefan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1552-5279 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
25 Jan 2023 12:33 |
Last Modified: |
27 Jul 2023 00:12 |
Publisher DOI: |
10.1002/alz.12915 |
PubMed ID: |
36588502 |
Uncontrolled Keywords: |
Alzheimer's disease apathy cost of illness dementia economics resource use |
BORIS DOI: |
10.48350/176755 |
URI: |
https://boris.unibe.ch/id/eprint/176755 |
Actions (login required)
 |
Edit item |