Learning direction selectivity through spike-timing dependent modification of neurotransmitter release probability

Buchs, Nissim J.; Senn, Walter (2001). Learning direction selectivity through spike-timing dependent modification of neurotransmitter release probability. Neurocomputing, 38-40, pp. 121-127. Elsevier 10.1016/S0925-2312(01)00547-1

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It has recently been proposed that the direction selectivity of simple cells emerges from an interplay of depressing and non-depressing synapses projecting in an asymmetric arrangement onto these cells. We show that such an asymmetric arrangement may develop from a temporally asymmetric spike-based learning rule. The rule redistributes the probability of vesicle discharge, producing synapses with high discharge probability and strong depression in one-half of the receptive field and low discharge probability and weak depression in the other. This spatial shift together with the temporal phase advance of the depressing synapses adds up with the response of the surrounding non-depressing synapses only when the stimulus moves in the preferred direction.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Physiology

UniBE Contributor:

Senn, Walter

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0925-2312

Publisher:

Elsevier

Language:

English

Submitter:

Virginie Sabado

Date Deposited:

18 Jan 2023 15:07

Last Modified:

18 Jan 2023 15:36

Publisher DOI:

10.1016/S0925-2312(01)00547-1

BORIS DOI:

10.48350/177232

URI:

https://boris.unibe.ch/id/eprint/177232

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