Rocha, Bruna P; Nakamura, Robertha C; Verardino, Gustavo; Leverone, Andreia; D'Almeida, Luiza F V; Azulay, Vitoria; Haneke, Eckart (2023). Histopathological analysis of chronic paronychia. International journal of dermatology, 62(4), pp. 514-517. Wiley 10.1111/ijd.16564
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BACKGROUND
Chronic paronychia is an inflammatory process of the nail folds lasting more than 6 weeks. Clinically, there is hypertrophy and retraction of the folds and absence of the cuticle. Treatment involves clinical measures and, when there is no response or the hypertrophy of the folds is very pronounced, surgical treatment is indicated. Post-surgical histopathology is little studied in the literature. In this sense, we believe that the histopathological study is important not only for the individualized understanding of the patient's chronic disease, avoiding relapses, but also for the understanding of its pathophysiology and treatment possibilities.
OBJECTIVE
To describe the histopathological changes found in biopsies of the proximal nail fold of patients with chronic paronychia undergoing surgical treatment.
MATERIALS AND METHODS
A histopathological study of 16 nail folds from 6 patients after surgery was performed at 2 study centers.
RESULTS
The most prevalent epidermal findings were orthokeratosis, hypergranulosis, acanthosis and spongiosis and the dermal findings were fibrosis and mononuclear inflammatory infiltrate.
CONCLUSION
The histopathological study allowed us to conclude that chronic paronychia is primarily an inflammatory process, but it is not possible to conclude whether microorganisms such as Candida and bacterial cocci are part of the etiology or just secondary and opportunistic agents.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Haneke, Eckart |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1365-4632 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
16 Jan 2023 11:37 |
Last Modified: |
16 Mar 2023 00:14 |
Publisher DOI: |
10.1111/ijd.16564 |
PubMed ID: |
36631425 |
BORIS DOI: |
10.48350/177264 |
URI: |
https://boris.unibe.ch/id/eprint/177264 |
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