Intravascular lithotripsy: a powerful tool to treat peripheral artery calcifications.

Vedani, Sébastien; Haligür, Didem; Jungi, Silvan; Bosiers, Michel J (2023). Intravascular lithotripsy: a powerful tool to treat peripheral artery calcifications. (In Press). The journal of cardiovascular surgery Edizioni Minerva Medica 10.23736/S0021-9509.22.12535-8

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Calcification represent one the most important predictors of treatment failure of endovascular therapy for peripheral arterial disease, since it restricts wall expansion and acts as a barrier for drug uptake. It also increases complications after PTA like dissection, perforation, and embolization with poor outcomes. Intravascular lithotripsy (IVL) is a novel approach for the treatment of vascular calcifications with the goal to optimize outcome in patients with PAD and heavy calcifications. This review gives an overview of the currently published articles regarding the use of IVL within the vascular field. In conclusion, IVL is a safe and effective approach in the treatment of highly calcified arteries with excellent results and low rates of related complications, such as embolization, dissection, and perforation. However, it seems to require adjunctive therapies to enhance long-term patency as well as an adequate sizing (1.1:1 ratio). Its use to facilitate access of large-bore devices seems to be valuable by changing vessel compliance and achieving luminal gain. Further studies are nonetheless mandatory.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery

UniBE Contributor:

Vedani, Sébastien Michel, Haligür, Didem, Jungi, Silvan, Bosiers, Michel Joseph Robert


600 Technology > 610 Medicine & health




Edizioni Minerva Medica




Pubmed Import

Date Deposited:

23 Jan 2023 13:02

Last Modified:

23 Jan 2023 23:28

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