Pape, Janna; Bajka, Anahita; Seifert, Burkhardt; Asmis, Lars; Imesch, Patrick; Metzler, Julian; Burkhardt, Tilo; Condous, George; Samartzis, Eleftherios Pierre; Bajka, Michael (2023). Judging Urgency in 343 Ectopic Pregnancies Prior to Surgery - The Importance of Transvaginal Sonographic Diagnosis of Intraabdominal Free Blood. Ultraschall in der Medizin, 44(6), pp. 614-622. Thieme 10.1055/a-1967-2134
Full text not available from this repository. (Request a copy)OBJECTIVES
Assessing urgency in ectopic pregnancies (ECP) remains controversial since the disorder covers a large clinical spectrum. Severe conditions such as acute abdomen or hemodynamic instability are mostly related to intra-abdominal blood loss diagnosed as free fluid (FF) on transvaginal sonography (TVS). The aims of the current study were to investigate the value of FF and to assess other potentially predictive parameters for judging urgency.
METHODS
Retrospective cohort analysis on prospectively collected cases of proven ECP (n = 343). Demographics, clinical and laboratory parameters, and findings on TVS and laparoscopy (LSC) were extracted from the digital patient file. FF on TVS and free blood (FB) in LSC were evaluated. Low urgency was defined as FB (LSC) < 100 ml and high urgency as FB (LSC) ≥ 300 ml. The best subset of variables for the prediction of FB was selected and predictors of urgency were evaluated using receiver operator characteristic (ROC) curves.
RESULTS
Clinical symptoms, age, β-HCG, hemoglobin (HB) preoperative, and FF were examined in multivariate analysis for the cutoff values of 100 ml and 300 ml. FF was the only independent predictor for low and high urgency; HB preoperative was only significant for high urgency offering marginal improvement. ROC analysis revealed FF as an excellent discriminatory parameter for defining low (AUC 0.837, 95% CI 0.794-0.879) and high urgency (AUC 0.902, 95 % CI 0.860-0.945).
CONCLUSION
Single assessment of FF on TVS is most valuable for judging urgency. However, the exact cutoff values for a low- and high-risk situation must still be defined.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology |
UniBE Contributor: |
Pape, Janna |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1438-8782 |
Publisher: |
Thieme |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
25 Jan 2023 15:39 |
Last Modified: |
06 Dec 2023 00:11 |
Publisher DOI: |
10.1055/a-1967-2134 |
PubMed ID: |
36657460 |
URI: |
https://boris.unibe.ch/id/eprint/177702 |
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