Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome.

Lutz, Katharina; Häni, Levin; Kissling, Cédric; Raabe, Andreas; Schucht, Philippe; Seidel, Kathleen (2023). Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome. Cancers, 15(3) MDPI AG 10.3390/cancers15030781

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OBJECTIVE

During surgery on low-grade gliomas (LGG), reliable data relevant to the primary motor cortex (M1) for the face area are lacking. We analyzed the impact of tumor removal within the M1 face area on neurological deficits.

METHODS

We included LGG patients with resection within the M1 face area between May 2012 and November 2019. The primary endpoint was postoperative facial motor function. Secondary endpoints were postoperative aphasia, dysarthria, and dysphagia. Surgery was performed either with the awake protocol or under anesthesia with continuous dynamic mapping. The alarm criteria were speech arrest or a mapping threshold of 3 mA or less. Resection was completed in five patients. The resection was stopped due to the alarm criteria in three patients and for other reasons (vascular supply, patient performance) in four patients. A total of 66.7% (n = 8) presented with new-onset facial paresis (62.5% left LGG) and 41.7% (n = 5) with aphasia (all left LGG) postoperatively. After one year, all eight patients had recovered from the facial paresis. Tumor removal within the M1 face area was not associated with permanent facial motor deficits.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery

UniBE Contributor:

Lutz, Katharina Sarah Jennifer, Häni, Levin, Kissling, Cédric Karl, Raabe, Andreas, Schucht, Philippe, Seidel, Kathleen

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2072-6694

Publisher:

MDPI AG

Language:

English

Submitter:

Pubmed Import

Date Deposited:

13 Feb 2023 16:05

Last Modified:

13 Feb 2023 23:27

Publisher DOI:

10.3390/cancers15030781

PubMed ID:

36765739

Uncontrolled Keywords:

GTR electrical stimulation face motor cortex glioma surgery intraoperative neurophysiological monitoring low-grade glioma motor evoked potentials

BORIS DOI:

10.48350/178692

URI:

https://boris.unibe.ch/id/eprint/178692

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