Boillat, Gwendoline; Franssen, Tim; Wanderer, Stefan; Rey, Jeannine; Casoni, Daniela; Andereggen, Lukas; Marbacher, Serge; Gruter, Basil E (2023). Anatomical Variations of the Common Carotid Arteries and Neck Structures of the New Zealand White Rabbit and Their Implications for the Development of Preclinical Extracranial Aneurysm Models. Brain Sciences, 13(2) MDPI 10.3390/brainsci13020222
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BACKGROUND
Rabbit models involving neck arteries are of growing importance for the development of preclinical aneurysm models. An optimal understanding of the anatomy is primordial to allow the conception of models while minimizing mortality and morbidity. The aim of this study is to give reliable anatomical landmarks to allow a standardized approach to the neck vessels.
METHODS
We performed a necropsy on nine specimens from ongoing experimental studies. We measured the distance between the origins of the right and left common carotid artery (rCCA/lCCA) and between the rCCA and the manubrium sterni (MS). The structures at risk were described.
RESULTS
Female New Zealand White rabbits (NZWR) weighing 3.7 ± 0.3 kg and aged 25 ± 5 weeks were included. The rCCA origin was located 9.6 ± 1.2 mm laterally and 10.1 ± 3.3 mm caudally to the MS. In all specimens, the lCCA originated from the aortic arch, together with the brachiocephalic trunk (BCT), and 6.2 ± 3.1 mm proximally to the rCCA origin. The external and internal jugular veins, trachea and laryngeal nerve were the main structures at risk.
CONCLUSIONS
The data help to localize both CCAs and their origin to guide surgical approaches with the manubrium sterni as a main landmark. Special attention has to be paid to the trachea, jugular veins and laryngeal nerves.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Neurochirurgie |
UniBE Contributor: |
Boillat, Gwendoline, Wanderer, Stefan, Casoni, Daniela, Andereggen, Lukas, Marbacher, Serge |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2076-3425 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
02 Mar 2023 12:20 |
Last Modified: |
10 May 2024 09:00 |
Publisher DOI: |
10.3390/brainsci13020222 |
PubMed ID: |
36831765 |
Uncontrolled Keywords: |
New Zeeland White Rabbit anatomy aneurysm animal model carotid arteries |
BORIS DOI: |
10.48350/179259 |
URI: |
https://boris.unibe.ch/id/eprint/179259 |
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