Mingels, Clemens; Weidner, Sabine; Sari, Hasan; Büsser, Dorothee; Zeimpekis, Konstantinos; Shi, Kuangyu; Alberts, Ian; Rominger, Axel (2023). Impact of the new ultra-high sensitivity mode in a long axial field-of-view PET/CT. Annals of nuclear medicine, 37(5), pp. 310-315. Springer 10.1007/s12149-023-01827-y
Full text not available from this repository. (Request a copy)OBJECTIVE
Long axial field-of-view (LAFOV) PET/CT showed improved performance resulting from higher sensitivity. The aim was to quantify the impact of using the full acceptance angle (UHS) in image reconstructions with the Biograph Vision Quadra LAFOV PET/CT (Siemens Healthineers) compared to the limited acceptance angle (high sensitivity mode, HS).
METHODS
38 oncological patients examined on a LAFOV Biograph Vision Quadra PET/CT were analysed. 15 patients underwent [18F]FDG-PET/CT, 15 patients underwent [18F]PSMA-1007 PET/CT, and 8 patients underwent [68Ga]Ga-DOTA-TOC PET/CT. Signal-to-noise ratio (SNR) and standardised uptake values (SUVmean/max/peak) were used to compare UHS and HS with different acquisition times.
RESULTS
The SNR was significantly higher for UHS compared to HS over all acquisition times (SNR UHS/HS [18F]FDG: 1.35 ± 0.02, p < 0.001; [18F]PSMA-1007: 1.25 ± 0.02, p < 0.001; [68Ga]Ga-DOTA-TOC: 1.29 ± 0.02, p < 0.001).
CONCLUSION
UHS showed significantly higher SNR opening the possibility of halving short acquisition times. This is of advantage in further reduction of whole-body PET/CT acquisition.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine |
UniBE Contributor: |
Mingels, Clemens, Weidner, Sabine Edith Martha, Büsser, Dorothee, Zeimpekis, Konstantinos, Shi, Kuangyu, Alberts, Ian Leigh, Rominger, Axel Oliver |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1864-6433 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Mar 2023 10:02 |
Last Modified: |
16 May 2023 00:14 |
Publisher DOI: |
10.1007/s12149-023-01827-y |
PubMed ID: |
36913094 |
Uncontrolled Keywords: |
Acquisition time High sensitivity LAFOV PET/CT Ultra-high sensitivity Whole-body PET/CT |
URI: |
https://boris.unibe.ch/id/eprint/179997 |
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