Weng, Guodong; Radojewski, Piotr; Slotboom, Johannes (2023). α-D-Glucose as a non-radioactive MRS tracer for metabolic studies of the brain. Scientific Reports, 13(1), p. 6159. Nature Publishing Group 10.1038/s41598-023-33161-8
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Changes in brain glucose metabolism occur in many neurological disorders as well as during aging. Most studies on the uptake of glucose in the brain use positron emission tomography, which requires injection of a radioactive tracer. Our study shows that ultra-high-field 1H-MRS can be used to measure α-D-glucose at 5.22 ppm in vivo, and the α-D-glucose can be used as a radiation-free tracer in the human brain.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology |
UniBE Contributor: |
Weng, Guodong, Radojewski, Piotr, Slotboom, Johannes |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2045-2322 |
Publisher: |
Nature Publishing Group |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
17 Apr 2023 11:11 |
Last Modified: |
23 Apr 2023 02:21 |
Publisher DOI: |
10.1038/s41598-023-33161-8 |
PubMed ID: |
37061615 |
BORIS DOI: |
10.48350/181759 |
URI: |
https://boris.unibe.ch/id/eprint/181759 |
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